Cough suppressants can come in immediate-release and extended-release preparations. American Society of Health-System Pharmacists, Inc. Disclaimer. Our Fact Sheets answer frequently asked questions about many common exposures during pregnancy and breastfeeding, including medications, recreational substances, cosmetic treatments, health conditions, infections, vaccines, and more. 3 Symptoms usually begin within 24 hours of an increased dose of a serotonergic agent, the addition of another serotonergic agent to Learn about the uses, side effects, and safety tips for diclofenac sodium. When used as a nasal decongestant, phenylephrine relieves a stuffy nose due to the common cold or other ailments. phenylephrine (Sudafed PE), pseudoephedrine (Sudafed) Less convenient, but safer, are the nasal salt water lavages such as saline nasal sprays Neti-pots (Considered safe in recommended dosages) Caution: Sudafed-like medications can speed up your heart rate; therefore, use caution if you have an underlying heart condition. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. Popular examples include pain relievers like acetaminophen and ibuprofen (Advil, Motrin), cough suppressants such as dextromethorphan and antihistamines like loratadine (Claritin 24H). Diclofenac sodium is commonly used in OTC medicines to temporarily relieve minor to moderate aches and pains caused by arthritis. Dextromethorphan HBr 5 mg (in each 5 mL) Phenylephrine HCl 2.5 mg (in each 5 mL) WEIGHT WEIGHT, AGE & DOSE* AGE: DOSE* Under 36 lbs: Under 4 years: Do not use. Phenylephrine HCl 5 mg . Veterinary use. Wal-Mart DayTime Cold and Flu Drug Facts. It is available over-the-counter alone and is also present in many over-the-counter and prescription combination medications. Acetaminophen: Acts on hypothalamus to produce antipyresis; may work peripherally to pain impulse generation; may also inhibit prostaglandin synthesis in CNS Chlorpheniramine: Histamine H1-receptor antagonist Dextromethorphan is a cough suppressant that acts centrally on the cough center in the medulla Phenylephrine is a vasoconstrictor and a decongestant that Lists the various brand names available for medicines containing dextromethorphan. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema. Phenylephrine also shrinks the swelling caused by hemorrhoids. 1 The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Norel DM (as a combination product containing Chlorpheniramine, Dextromethorphan, Phenylephrine)see Phenylephrine; Norel SR (as a combination product containing Acetaminophen, Chlorpheniramine, Phenylephrine, Phenyltoloxamine)see Phenylephrine; Norethindrone; Norethisteronesee Elagolix, Estradiol, and Norethindrone Sign Up OTC drugs are medications that are safe and effective for use by the general public without seeking treatment by a health professional. Pain Find information on acetaminophen use, treatment, drug class and molecular formula. Talk with the doctor before giving Mucinex Sinus-Max (acetaminophen, dextromethorphan, guaifenesin, phenylephrine caps & tabs) to a child. Do not use this medicine without a doctor's advice if you are breast-feeding a baby. Phenylephrine Hydrochloride 5 mg: Nasal Decongestant: NIGHTTIME Tablets (each Blue tablet contains) Medicinal ingredients: Purpose: Acetaminophen (extra strength) 500 mg: Pain reliever, fever reducer: Dextromethorphan Hydrobromide 10 mg: Cough Suppressant: Phenylephrine Hydrochloride 5 mg: 20 mg of dextromethorphan (a cough suppressant) 10 mg of phenylephrine (a nasal decongestant) The active ingredients in NyQuil Cold and Flu Nighttime Relief Liquid per 30 mL are: 650 mg of acetaminophen (a pain and fever reducer) 20 mg of dextromethorphan (a cough suppressant) 12.5 mg of doxylamine (a sedating antihistamine) Decongestants may also slow breast milk production. Location Function; cardiac myocytes: K ir channels close upon depolarization, slowing membrane repolarization and helping maintain a more prolonged cardiac action potential.This type of inward-rectifier channel is distinct from delayed rectifier K + channels, which help repolarize nerve and muscle cells after action potentials; and potassium leak channels, which provide much of the Lists the various brand names available for medicines containing pseudoephedrine. 48-95 lbs: 6-11 years: 10 mL. Tweel explains the most common active ingredient in over-the-counter cough suppressants is dextromethorphan, abbreviated as DM at the end of many brand names. see Aluminum Hydroxide and Magnesium Hydroxide M-Clear WC (as a combination product containing Codeine, Guaifenesin)see Codeine; M-End PE (as a combination product containing Brompheniramine, Codeine, Phenylephrine)see Codeine; M-M-R II (as a combination product containing Measles Vaccine, Mumps Vaccine, Rubella Vaccine)see MMR Vaccine Phenylephrine: Sympathomimetic decongestant: C: Yes Dextromethorphan is a nonnarcotic antitussive isomer of codeine that was found to be teratogenic in chicken embryos. Dextromethorphan: Antitussive: Cough (wet or productive) Guaifenesin: Expectorant: Fever: Acetaminophen, aspirin, ibuprofen, naproxen: Analgesic: Headache: Sudafed PE (phenylephrine): It's available as a tablet, liquid, and quick dissolve strip, and also in combination cold medicines. Available in: If you take an MAOI, you should not take cold, flu, or cough medicine that contains a decongestant (such as phenylephrine and pseudoephedrine) or dextromethorphan. Find information on pseudoephedrine use, treatment, drug class and molecular formula. Many reports prefer to call this serotonin toxicity rather than syndrome due to its wide range of symptoms and toxicity. Learn how to cite this page. Warnings. Dextromethorphan HBr 10 mg . Nasal decongestant sprays are also not safe to use if you are taking an MAOI. Visit our complete library of health topics, with coverage information, policies and more. Browse Drugs and Medicines. 2 Phenylephrine was granted FDA approval in 1939. 36-47 lbs: 4-5 years: Do not use unless directed by a doctor. Monographs cover generic and brand name, drug class and mechanism, dosing, drug interactions, side effects,and use. Aspirin. Donatussin Drops (containing Guaifenesin, Phenylephrine) Zyncof (containing Dextromethorphan, Guaifenesin) Last Revised - 01/15/2022. Nausea and Vomiting Vitamin B6 25mg 3 times per day plus doxalamine succinate ( Unisom ) 25mg up to three times per day. Do not give dextromethorphan to a child younger than 4 years old. Answers to Your Frequently Asked Questions about Pregnancy & Breastfeeding Exposures. Phenylephrine, present in Sudafed PE, Dextromethorphan (DXM) is a cough suppressant present in many cold and flu medicines. Phenylephrine (phenylephrine hydrochloride) What is phenylephrine? Vaginal Yeast Infection Miconazole (Monistat) 1 Index of comprehensive articles on common prescription and OTC medications and drugs, p listing. OTC drugs are medications that are safe and effective for use by the general public without seeking treatment by a health professional. Find information on dextromethorphan use, treatment, drug class and molecular formula. Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension, 6,8 dilate the pupil, 7 and induce local vasoconstriction. Dextromethorphan is a cough suppressant used in OTC medications such as Robitussin to reduce coughing. PediaCare Children's Allergy and Cold (containing Diphenhydramine, Phenylephrine) Robitussin Night Time Cough and Cold (containing Diphenhydramine, Phenylephrine) Sudafed PE Day/Night Cold (containing Acetaminophen, Dextromethorphan, Diphenhydramine, Guaifenesin, Phenylephrine) Guaifenesin is used to try to help with coughing up thick mucus and is sometimes combined with dextromethorphan, an antitussive (cough suppressant), and decongestants such as ephedrine, pseudoephedrine, or phenylephrine. Phenylephrine, present in Sudafed PE, Dextromethorphan (DXM) is a cough suppressant present in many cold and flu medicines. PRESENTATION. Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, and phenylephrine, any of which can cause permanent bodily damage such as kidney failure, or even death, if taken on the generally accepted recreational dosing scale of dextromethorphan. Popular examples include pain relievers like acetaminophen and ibuprofen (Advil, Motrin), cough suppressants such as dextromethorphan and antihistamines like loratadine (Claritin 24H). Topical phenylephrine hemorrhoidal gel (Preparation H or Anusol ) Witch hazel pads . It acts on parts of the brain to stop a person from coughing. Triaminic Day Time Cold and Cough (as a combination product containing Dextromethorphan, Phenylephrine)see Phenylephrine; Triaminic Day Time Cold and Cough (as a combination product containing Dextromethorphan, Phenylephrine)see Dextromethorphan; Triaminic Long-Acting Cough see Dextromethorphan The Journal of Emergency Medicine is an international, peer-reviewed publication featuring original contributions of interest to both the academic and practicing emergency physician.JEM, published monthly, contains research papers and clinical studies as well as articles focusing on the training of emergency physicians and on the practice of emergency medcine. Purpose. Pseudoephedrine and phenylephrine are available over the counter as Sudafed and are safe for many women to use during pregnancy. Active ingredients (in each softgel) Acetaminophen 325 mg . The presentation of serotonin syndrome is extremely variable, ranging from mild symptoms to a life-threatening syndrome. Alka-Seltzer Plus Night Cold Formula (containing Aspirin, Dextromethorphan, Doxylamine, Phenylephrine) Children's Dimetapp Cold and Cough (containing Brompheniramine, Dextromethorphan, Phenylephrine) Children's Dimetapp Multisymptom Cold and Flu (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine) M.A.H. Artificially sweetened liquid medicine may contain phenylalanine. Generic Name Phenylephrine DrugBank Accession Number DB00388 Background. Guaifenesin's neurological properties first became known in the late 1940s. Acetaminophen, dextromethorphan, guaifenesin, and phenylephrine may pass into breast milk and may harm a nursing baby. Lists the various brand names available for medicines containing acetaminophen. Lists the various brand names available for medicines containing chlorpheniramine. The active ingredients are dextromethorphan, guaifenesin, and phenylephrine. Different brands of Mucinex Sinus-Max (acetaminophen, dextromethorphan, guaifenesin, phenylephrine caps & tabs) may be for use in different ages of children. Dextromethorphan is used to treat a cough. Coldatrexy . Ingredients: ACETAMINOPHEN 325mg, DEXTROMETHORPHAN HYDROBROMIDE 10mg, PHENYLEPHRINE HYDROCHLORIDE 5mg Labeler: Wal-Mart Stores Inc NDC Code: 49035-215. Find information on chlorpheniramine use, treatment, drug class and molecular formula. It acts on parts of the brain to stop a person from coughing. Chemical formula: C9H8O4 Drugbank ID: DB00945 ATC codes: B01AC56, C10BX04, M01BA03, N02BA71, C10BX06, N02BA51, C10BX05, B01AC06, N02BA01, C10BX02, A01AD05, C10BX08, C10BX01 The information below refers to products available in the United States that contain aspirin.. Products containing aspirin aspirin systemic Phenylephrine is an active ingredient that has different uses in over-the-counter (OTC) medicines. Robitussin cough and cold is one brand example of a cough suppressant.